Canadian research into Rett syndrome is very well represented on the international stage. There are at least 20 different scientists or clinicians located in British Columbia, Alberta, Manitoba, Ontario and Quebec currently conducting projects relevant to Rett syndrome. In 2006, the Canadian Rett Syndrome Research Consortium was formed. As a result, there is a strong collaborative effort between Canadian researchers. In 2008, the first “team-based” research grant application was submitted to the Canadian government. Since inception, O.R.S.A. has financially supported the Consortium. Over two decades, the Association has provided numerous individual research grants across Canada, as it is deeply committed to supporting and funding Canadian research into Rett syndrome.